Author/Authors :
jumaa, maisaa g. misan university - college of medicine, Iraq , habib, khalid a. university of baghdad - college of science for women - biology department, baghdad, iraq , hussein, munther j. institute of liver studies - king s college hospital, London, UK
Abstract :
Epithelial ovarian cancer is the leading cause of cancer deaths from gynecological malignancies. Angiogenesis is considered essential for tumor growth and the development of metastases. VEGF and IL−8 are potent angiostimulatory molecules and their expression has been demonstrated in many solid tumors, including ovarian cancer. VEGF and IL-8 concentrations were measured by ELISA test (HumanVEGF,IL-8). Bioassay ELISA/ US Biological / USA). The median VEGF and IL-8 levels were significantly higher in the sera of ovarian cancer patients than in those with benign tumors and in healthy controls. Pretreatment VEGF and IL-8 serum levels might be regarded as an additional tool in the differentiation of ovarian tumors.
Keywords :
Ovarian cancer , VEGF , IL8 , Serum
