Author/Authors :
Amarante, M.P.F. Federal University of Ceara - Center of Hematology and Hemotherapy of Ceara, Faculty of Medicine, Brazil , Rocha Filho, F.D. Federal University of Ceara - Faculty of Medicine - Department of Pathology, Brazil , Castro, A.J.M. Federal University of Ceara - Center of Hematology and Hemotherapy of Ceara, Faculty of Medicine, Brazil , Silva Junior, G.B. Federal University of Ceara - Center of Hematology and Hemotherapy of Ceara, Faculty of Medicine, Brazil , da Silva Herivaldo, F. Federal University of Ceara - Center of Hematology and Hemotherapy of Ceara, Faculty of Medicine, Brazil
Abstract :
A 27-year-old woman presented with a 6-month history of a painful and erosive lesion in the hard palate with a progressive increase in size. Examination indicated two ulcerated lesions in the hard palate. Histopathology showed dense exudation of atypical mononuclear leukocytes composed of small and medium lymphoid cells with round or oval nuclei. Immunohistochemistry showed abnormal T-cell population with strong expression for CD45RO and CD7 with negativity for CD20 and certain T antigenic loss, suggesting T-cell lymphoma. Serology for the Epstein– Barr virus was positive. This is the second case of nasal extranodal T/NK-cell lymphoma presenting as a palatal ulcer reported to date.
Keywords :
Epstein–Barr virus , immunohistochemistry , nasal extranodal T , NK lymphoma
