Title of article
Nasal extranodal T/NK-cell lymphoma presenting as a palatal lesion: an uncommon clinical presentation of a rare disease
Author/Authors
Amarante, M.P.F. Federal University of Ceara - Center of Hematology and Hemotherapy of Ceara, Faculty of Medicine, Brazil , Rocha Filho, F.D. Federal University of Ceara - Faculty of Medicine - Department of Pathology, Brazil , Castro, A.J.M. Federal University of Ceara - Center of Hematology and Hemotherapy of Ceara, Faculty of Medicine, Brazil , Silva Junior, G.B. Federal University of Ceara - Center of Hematology and Hemotherapy of Ceara, Faculty of Medicine, Brazil , da Silva Herivaldo, F. Federal University of Ceara - Center of Hematology and Hemotherapy of Ceara, Faculty of Medicine, Brazil
From page
44
To page
48
Abstract
A 27-year-old woman presented with a 6-month history of a painful and erosive lesion in the hard palate with a progressive increase in size. Examination indicated two ulcerated lesions in the hard palate. Histopathology showed dense exudation of atypical mononuclear leukocytes composed of small and medium lymphoid cells with round or oval nuclei. Immunohistochemistry showed abnormal T-cell population with strong expression for CD45RO and CD7 with negativity for CD20 and certain T antigenic loss, suggesting T-cell lymphoma. Serology for the Epstein– Barr virus was positive. This is the second case of nasal extranodal T/NK-cell lymphoma presenting as a palatal ulcer reported to date.
Keywords
Epstein–Barr virus , immunohistochemistry , nasal extranodal T , NK lymphoma
Journal title
The Egyptian Journal of Haematology
Journal title
The Egyptian Journal of Haematology
Record number
2693751
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