Title of article :
The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review
Author/Authors :
Sculean, Anton Radboud University - Medical Center - Department of Periodontology, Netherlands , Schwarz, Frank Heinrich Heine University - Department of Oral Surgery, Germany , Becker, Jürgen Heinrich Heine University - Department of Oral Surgery, Germany , Brecx, Michel Radboud University - Medical Center - Department of Periodontology, Netherlands
Abstract :
Regenerative periodontal therapy aims at reconstitution of the lost periodontal structures such as new formation of root cementum, periodontal ligament and alveolar bone. Findings from basic research indicate that enamel matrix protein derivative (EMD) has a key role in periodontal wound healing. Histological results from animal and human studies have shown that treatment with EMD promotes periodontal regeneration. Moreover, clinical studies have indicated that treatment with EMD positively influences periodontal wound healing in humans. This review aims to present an overview of evidence-based clinical indications for regenerative therapy with EMD.
Keywords :
Enamel matrix protein derivative , Cementogenesis , Regenerative periodontal therapy , Emdogain , review
Journal title :
Medical Principles and Practice
Journal title :
Medical Principles and Practice
