Title of article :
Case Report: Rectal Carcinoma in a Young Female Patient with Peutz-Jeghers Syndrome
Author/Authors :
Tsai, Hsiang-Lin Kaohsiung Medical University - Departments of Surgery and Cancer Center, Taiwan , Lin, Chih-Hung Kaohsiung Medical University - Department of Pathology, Taiwan , Cheng, Ya-Lin Kaohsiung Medical University - Department of Surgery, Taiwan , Huang, Ching-Wen Kaohsiung Medical University - Department of Surgery, Taiwan , Wang, Jaw-Yuan Kaohsiung Medical University - Institute of Clinical Medicine - Departments of Surgery and Pathology and Cancer Center, Taiwan
Abstract :
Objective: To report a case of rectal cancer in a patient with Peutz-Jeghers syndrome (PJS). Clinical Presentation and Intervention: A 20-year-old woman with intermittent bloody stool of 4 months was admitted for examination. Gastroendoscopy revealed multiple polyps involving the stomach, small intestine, colon and a rectal adenocarcinoma. A diagnosis of PJS was made based on intestinal polyps with characteristic pathology and melanotic macules on the lips. After surgery and chemotherapy upon follow-up at 8 months, the patient did not have any signs of recurrence. Conclusion: This case showed that rectal carcinoma should be considered for young patients with PJS.
Keywords :
Peutz , Jeghers syndrome , Rectal carcinoma , Cancer risk , Hamartomatous polyp , Intussusception
Journal title :
Medical Principles and Practice
Journal title :
Medical Principles and Practice
