Title of article :
PHYTOCHEMICAL AND BIOLOGICAL STUDY OF PETREA VOLUBILIS L. (VERBENACEAE)
Author/Authors :
Abdelwahab, M. F. Minia University - Faculty of Pharmacy - Department of Pharmacognosy, Egypt , Abdel-Lateff, A. King Abdul-Aziz University - Jeddah Community College - Department of Health Information Technology, Saudi Arabia , Fouad, M. A. Minia University - Faculty of Pharmacy - Department of Pharmacognosy, Egypt , Desoukey, S. Y. Minia University - Faculty of Pharmacy - Department of Pharmacognosy, Egypt , Kamel, M. S. Minia University - Faculty of Pharmacy - Department of Pharmacognosy, Egypt
Abstract :
Petrea volubilis L. was studied for its secondary metabolites and biological activities. The phytochemical screening of dried aerial parts revealed the presence of different constituents such as unsaturated sterols, triterpens, and flavonoids. The biological activities of the total extract and different fractions were evaluated in a series of bioassays (antioxidant, antiinflammatory, analgesic, antipyretic and antibacterial), the majority of them showed significant activities in the applied test systems. Extensive purification of the ethyl acetate extract led to isolation of apigenin (1), quercetin (2), 4`, 6-dimethylscutellarien (3), hypogallic acid (3,4- dihydroxybenzoic acid) (4), trans-caffeic acid (5) vanillic acid (6) and acteoside (7). The structure elucidation of 1-7, was carried out by 1H-NMR, UV and MS analyses.
Journal title :
Bulletin Of Pharmaceutical Sciences, Assiut University
Journal title :
Bulletin Of Pharmaceutical Sciences, Assiut University
