• Title of article

    CARBIMAZOLE-INDUCED APLASTIC ANAEMIA–A CASE REPORT

  • Author/Authors

    Vijay, AP university of malaya - Faculty of Medicine - Department of Medicine (Endocrinology), Malaysia , Lim, SS university of malaya - Faculty of Medicine - Department of Medicine (Endocrinology), Malaysia , Tan, ATB university of malaya - Faculty of Medicine - Department of Medicine (Endocrinology), Malaysia , Rokiah, P university of malaya - Faculty of Medicine - Department of Medicine (Endocrinology), Malaysia , Chan, SP university of malaya - Faculty of Medicine - Department of Medicine (Endocrinology), Malaysia

  • From page
    92
  • To page
    95
  • Abstract
    Antithyroid drugs have been used for more than 50 years for the management of hyperthyroidism. Most patients tolerate treatment well, but some may develop rare life threatening side effects such as agranulocytosis and aplastic anaemia. Clinical experience with the latter condition is extremely limited. We report on a case of carbimazole-induced aplastic anaemia caused by hypocellular bone marrow and associated plasmacytosis in a thyrotoxic patient chronically treated with carbimazole. This resolved after substitution with propylthiouracil. The clinical course was complicated by neutropaenic septicaemia and atrial fibrillation.
  • Keywords
    thyrotoxicosis , carbimazole , aplastic anaemia , plasmacytosis
  • Journal title
    Journal Of Health an‎d Translational Medicine
  • Journal title
    Journal Of Health an‎d Translational Medicine
  • Record number

    2697993

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2697993