Title of article :
Phase-Transfer Catalyzed Alkylation of Hydantoin and 5-Methyl-5-Phenylhydantoin
Author/Authors :
Sobahi, Tariq R. King Abdulaziz University - Faculty of Science - Department of Chemistry, Saudi Arabia , Hassan, Mohamed A. King Abdulaziz University - Faculty of Science - Department of Chemistry, Saudi Arabia , Moustafa, Huissen A. King Abdulaziz University - Faculty of Science - Department of Chemistry, Saudi Arabia , Bawaked, Nahed O. King Abdulaziz University - Faculty of Science - Department of Chemistry, Saudi Arabia
Abstract :
PTC-alkylation of hydantoin (1a) and 5-methyl-5-phenylhydantoin(1b) by different organohalogen reagents at 25ºC in thepresence of tetrabutylammonium bromide as catalyst has been investigatedeither in the absence or presence of CS2. This work is aimingto study the comparative reactivity of N- versus O- of hydantoinstoward alkylation and cycloalkylation. In all cases N3 monoalkylationor N1 and N3 dialkylation are the main products. The structures ofalkylhydantoins have been established by IR, NMR, mass spectral data and elemental analysis
Keywords :
Phase , transfer catalysis (PTC) , alkylation , cycloalkylation , hydantoin , 5 , methyl , 5 , phenylhydantoin , tetrabutylammonium bromide
Journal title :
Journal of King Abdulaziz University : Science
Journal title :
Journal of King Abdulaziz University : Science
