Title of article :
Using Nigella sativa Oil to Treat and Heal Chemical Induced Wound of Rabbit Skin
Author/Authors :
Abu-Zinadah, Osama A. King Abdulaziz Univ. - Faculty of Science - Dept of Biological Sciences, Saudi Arab
Abstract :
The aim of this study is to evaluate the efficacy of Nigellasativa oil (NSO) to accelerate the repairing of wound healing in burnwound model using local rabbits as experimental animals. Prematurerabbits are chemically burned by concentrated HCl, and then theydivided into three groups, control and topically treated ones (5 animalseach). One of the treated groups was topically treated by antibiotic(Baneocin), while the other was treated by NSO. The contractingability was evaluated by the reducing width of wounds daily. It wasobserved that the contracting ability of the wounds treated by (NSO)is similar to that of the antibiotic. However, there was somewhatretardation in wound treated with NSO. The closure time of thewounds of both was more or less similar. However, the hair growingtime was the same in both treated groups. Histologically, theperipheries of the wounds grow rapidly in treated groups without anycontamination by microbes. The present results support the use ofsuch NSO in topical skin care and healing wounds.
Journal title :
Journal of King Abdulaziz University : Science
Journal title :
Journal of King Abdulaziz University : Science