Author/Authors :
Mokhtarpour Neilagh, Akbar Department of Dermatology - School of Medicine - Urmia University of Medical Sciences - Urmia, Iran , Sadeghilar, Majid Department of Dermatology - School of Medicine - Urmia University of Medical Sciences - Urmia, Iran , Aghazadeh Barenji, Mehdi Department of Dermatology - School of Medicine - Urmia University of Medical Sciences - Urmia, Iran , Behrouz Sharif, Shahin Department of Medical Genetics - Faculty of Medicine - Tabriz University of Medical Sciences - Tabriz, Iran , Sedokani, Amin Department of Cardiology - School of Medicine - Seyedoshohada Hospital - Urmia University of Medical Sciences - Urmia, Iran
Abstract :
As a chronic, immune-mediated skin disorder,
psoriasis affects approximately 2-4% of people 1.
Pustular, erythrodermic, guttate psoriasis, and
psoriasis vulgaris comprise frequent forms of
the disease, while psoriatic arthritis has been
described as a rare form. Patients might suffer
from itchy and/or painful lesions and although
its exact pathogenesis is not well established,
abnormal differentiation and hyperproliferation of
keratinocytes, increased epidermal cell turnover,
and infiltration of inflammatory cells have been
suggested as its characteristics, with inflammatory
cytokines also having been implicated to be
involved in psoriatic lesions.
