Title of article :
Adult Type – Chronic Myeloid Leukemia in Childhood: A Case Report and Review of Literature
Author/Authors :
Nikumbh, Dhiraj B. Medical Sciences University - Krishna Institute - Department of Pathology, India , Wader, J V Medical Sciences University - Krishna Institute - Department of Pathology, India , Kshirsagar, V Y Krishna Hospital Medical Research Center - Department of Pediatrics, India , Desai, S R Krishna Institute of Medical Sciences University - Department of Pathology, India , Jagtap, S V Medical Sciences University - Krishna Institute - Department of Pathology, India , Khedkar, J K Medical Sciences University - Krishna Institute - Department of Pathology, India
Abstract :
Background: In pediatric patients, chronic myeloid leukemia (CML) accounts for 2 to 5% of all the leukemia s but has an incidence of less than 1 case per 1,00,000 population younger than 20 years of age per year. CML is a clonal hematopoietic stem cell disorder. As per WHO classification, CML is included in Myelodysplastic/Myeloproliferative disorder. Adult type - CML is extremely rare in childhood.Case history: We report one such a case of Adult type of CML in an 11 year old male patient with chief complaints of abdominal distension since 1 month and cough with fever since 4-5 days. The clinical differential diagnosis was malaria, storage disorder or tropical splenomegaly. Though biological behaviour and prognosis are identical to that of adult type, we are reporting this case because of its extremely uncommon incidence
Keywords :
Chronic myeloid leukemia (CML) , adult type CML , childhood leukemia
Journal title :
Journal of Krishna Institute of Medical Sciences University (JKIMSU)
Journal title :
Journal of Krishna Institute of Medical Sciences University (JKIMSU)
