Title of article :
Synthesis, physicochemical, thermal, computationand DNA binding evaluation of trans-[CuBr_2(Me_2NCH_2CH_2NH_2)_2] complex
Author/Authors :
abdoh, muneer an-najah national university - science college - department of physics, Nablus, Palestine , essa, reeta an-najah national university - biology and biotechnology department, Nablus, Palestine , sawafta, ashraf an-najah national university - biology and biotechnology department, Nablus, Palestine , al-nuri, mohammed an-najah national university - department of chemistry, Nablus, Palestine , abu libdeh, aminah an-najah national university - biology and biotechnology department, Nablus, Palestine , al ali, anas an-najah national university - department of chemistry, Nablus, Palestine , al-zaqri, nabil king saud university - college of science - department of chemistry, Riyadh, Saudi Arabia , kumara, karthik university of mysore - department of studies in physics, Mysore, India , zarrouk, abdelkader université mohammed premier - faculté des sciences d’oujda - laboratoire de chimie appliquée et environnement (lcae-urac18), Oujda, Morocco , warad, ismail an-najah national university - department of chemistry, Nablus, Palestine
Abstract :
Asymmetrical Me_2NCH_2CH_2NH_2/copper(II)/bromide complex was synthesized in a good yield under ultrasonic vibration mode. The desired complex was characterized using, elemental EA, conductometric, UV-Vis, FTIR, MS and EDX analysis. The thermal behaviour of the complex was performed by TG. DFT calculations in order to investigate the complex structure parameters. The absorption and viscosity titration measurements reflected the desired complex as strong intercalate DNA-binder with high Kb binding constant value.
Keywords :
Copper(II) , Spectral , DFT , Thermal , DNA binding
