Author/Authors :
Tavallaii, Z ferdowsi university of mashhad, مشهد, ايران , Sabzevari, O ferdowsi university of mashhad, مشهد, ايران , Bakavoli, M ferdowsi university of mashhad, مشهد, ايران , Rahimizadeh, M ferdowsi university of mashhad, مشهد, ايران
Abstract :
A convenient one-pot preparation of 2-(alkylamino) and 2-(arylamino)-4(3H) quinazolinones in high yields has been developed by microwave induced heterocyclization of 2-aminobenzamide with isothiocyanates (or Isocyanates) in solvent-free conditions. In comparison, the reactions are faster under microwave irradiation and the yields are much higher than those by/of conventional heating (under reflux in toluene)