An Investigation of Intoxicated Patients who Underwent Hemodialysis: A-five Year Cross-sectional study

Background: Hemodialysis is one of the most common extracorporeal procedures that is used for treatment in some intoxicated patients. Therefore, epidemiology and prognostic factors in hemodialysis intoxicated patients were evaluated. Methods: In this cross-sectional study, all hospitalized patients, who underwent hemodialysis admitted to the poisoning center at Taleghani Hospital, Urmia, Iran, from 2016-2020 were evaluated. The demographic data, clinical and some laboratory findings in survivor and non-survivor group were studied retrospectively and evaluated in relation to outcome of the patients. Then, the data were analyzed by descriptive and analytical statistics using SPSS v 16. Results: In this study, 200 (158 males, 42 females) patients were evaluated. The mortality rate was 31.5% (79% males, 21% females). Toxic Alcohol (methanol, ethylene glycol) 86 (43%) and paraquat 58 (29%) were the main causes of poisoning among the patients treated with hemodialysis. Loss of consciousness 82 (41%) and Gastrointestinal discomforts (nausea, vomiting, and epigastric pain) 68 (34%) were the most signs and symptoms in patients. Statistically significant relationships (p value < 0.05) were found between the acute renal failure and causes of poisoning. Finally, 137 patients (68.5%) were discharged with full recovery and 63 cases (31.5%) were died. Conclusion: Because extracorporeal therapies such as hemodialysis are one of the main procedures in the treatment of poisoning and there are limited studies on the prevalence of hemodialysis in poisoned patients, this study was carried out to evaluate hemodialysis in intoxicated patients whose data can be used more widely in the future. However, more studies are required to explore the prevalence of hemodialysis in poisoned patients