Author/Authors :
Heshmatnia, Jalal Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases (NIRTLD) - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mirenayat, Maryam Sadat Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases (NIRTLD) - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Rezaei, Mitrasadat Pathology Department - School of Medicine - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Bongomin, Felix Division of Infection - Immunity and Respiratory Medicine - Faculty of Biology - Medicine and Health - The University of Manchester, Manchester, UK , Bakhshayeshkaram, Mehrdad Pediatric Respiratory Diseases Research Centre (PRDRC) - National Research Institute of Tuberculosis and Lung Diseases (NIRTLD) - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Tabarsi, Payam Clinical Tuberculosis and Epidemiology Research Center - National Research Institute of Tuberculosis and Lung Diseases (NIRTLD) - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Sheikhy, Kambiz Tracheal Diseases Research Center (TDRC) - National Research Institute of Tuberculosis and Lung Diseases (NIRTLD) - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mortezaee, Vida Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases (NIRTLD) - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
Pulmonary lymphangioleiomyomatosis (LAM) is an uncommon disease principally affecting women during childbearing years and eventually leading to progressive respiratory failure. Lung transplantation is a viable option for patients with end-stage disease. LAM-related complications remain common, but recurrence of LAM following allograft transplantation is rare. We present a 25-year-old woman who presented with progressive dyspnea five years after bilateral lung transplantation for end-stage LAM. Histological examination of transbronchial lung biopsy sample confirmed recurrent LAM. We changed cyclosporine to sirolimus and she is currently being considered for re-transplantation.
