Author/Authors :
Davoudi, Zahra Skull Base Research Center - Loghman Hakim Medical Center - Shahid Beheshti University of Medical Sciences, Tehran , Chouhdari, Arezoo Skull Base Research Center - Loghman Hakim Medical Center - Shahid Beheshti University of Medical Sciences, Tehran , Taherkhani, Adineh Department of Internal Medicine - Loghman Hakim Medical Center - Shahid Beheshti University of Medical Sciences, Tehran , Bidari Zerehpoosh, Farahnaz Department of Pathology - Shahid Beheshti University of Medical Sciences, Tehran , Samadian, Mohammad Skull Base Research Center - Loghman Hakim Medical Center - Shahid Beheshti University of Medical Sciences, Tehran
Abstract :
Background: Germinoma is a rare lesion found commonly in the pineal and suprasellar
regions of the brain. Clinical presentation mainly involves the location and size of the tumor
and the patient age. Endocrine abnormalities are the most common symptom.
Case Presentation: The patient was a 26-year-old Iranian female who suffered from
germinoma for a long time and was referred to Loghman Hakim Hospital for amenorrhea,
polyuria, and polydipsia. Despite diagnostic challenges, she was finally diagnosed with
suprasellar germinoma after endoscopic transsphenoidal surgery, followed by radiotherapy
and medical interventions to complement the surgery.
Conclusion: It is important to be able to diagnose the patient's problem at an early stage
based on their history, hormonal profile, laboratory results and radiological view.