Author/Authors :
Kamrani, Ghodsieh Department of Pathology - Cancer Research Institute - Babol University of Medical Science, Babol , Nikbakhsh, Novin Department of surgery - Cancer Research Institute - Babol University of Medical Sciences, Babol , Hosseini, Akram Department of Pathology - Cancer Research Institute - Babol University of Medical Science, Babol , Ghorbani, Hossein Department of Pathology - Cancer Research Institute - Babol University of Medical Science, Babol , Arefisigaroud, Niloufar Department of Pathology - School of medicine - Babol University of Medical Sciences, Babol , Davarian, Ali Ischemic Disorders Research Center - Golestan University of Medical Science, Gorgan
Abstract :
Background: Mucinous cystadenocarcinoma is a relatively uncommon histological subtype
of breast cancer that is a cystic form of papillary mucinous carcinoma. It is regularly
negative for estrogen and progesterone receptors and it is most often diagnosed in older than
55-60 years old. The incidence of breast mucinous cystadenocarcinoma is about 1-6% of
primary breast cancers. Here, we present a case of breast mucinous cystadenocarcinoma of
left breast in a 69-year-old female which is positive for estrogen and progesterone receptors.
Case Presentation: In this article, we describe a case of a-69-year-old female with a painful
mass in her left breast. Based on intraoperative pathology consult, neoplastic tissue mostly
floating in mucinous lakes with invasion to surrounding stroma was seen.
Immunohistochemistry profile showed positive estrogen and progesterone receptors and
negative for HER2.
Conclusion: Mucinous cystadenocarcinoma of breast is typically triple negative for
hormone receptors. But ER and PR positive variant of this tumor is rare, giving the chance
of a better prognosis for the patient with hormonal therapy.
Keywords :
Breast cancer , Mucinous cystadenocarcinoma , Estrogen receptor , Progesterone receptor
