Title of article :
The effect of narrowband ultraviolet B phototherapy on serum folate level
Author/Authors :
Shirzadian Kebria, Azar Department of Dermatology - Yahyanejad Hospital - Babol University of Medical Sciences, Babol , Hosseini, Meghdad Infertility and Reproductive Health Research Center - Health Research Institute - Babol University of Medical Sciences, Babol , Khafri, Sorayya Infertility and Reproductive Health Research Center - Health Research Institute - Babol University of Medical Sciences, Babol
Abstract :
Background: Narrowband ultraviolet B (NB-UVB) phototherapy has been used as a
common treatment for dermatologic diseases such as psoriasis and vitiligo and generally
considered a safe form of therapy during pregnancy. Invitro photodegradation of folate after
exposure to UVB radiation has been documented but studies on UVB-induced alternation
of serum folate level have reported inconsistent results. The aim of this study was to
investigate the effect of NB-UVB radiation on serum folate level.
Methods: In this study, serum folate levels were evaluated in patients at baseline and after
30 sessions of NB-UVB irradiation.
Results: Twenty patients completed the study: 10 psoriasis, 7 vitiligo and 3 mycosis
fungoides (patch stage). Mean serum folate level had significantly decreased from 2.76±0.59
ng/ml at baseline to 1.34±0.15 ng/ml after 30 sessions. (Mean NB-UVB cumulative dose
40.35±16.80 j/cm2, P=0.001).
Conclusion: Serum folate levels may decrease after long-term NB-UVB phototherapy in
patients with skin disorders.
Keywords :
Diabetic peripheral neuropathy , Nortriptyline , Duloxetine , Diabetes , Pain
Journal title :
Caspian Journal of Internal Medicine (CJIM)
