Author/Authors :
Sherafati, Alborz Department of Cardiology - School of Medicine - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences , Eslami, Masoud Department of Cardiology - School of Medicine - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences , Mollazadeh, Reza Department of Cardiology - School of Medicine - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences
Abstract :
J wave syndrome is an electrical disease of the heart due to pathologic early repolarization. It
encompasses a clinical spectrum from aborted sudden cardiac death due to ventricular
arrhythmia (VA) usually in young affected patients to self-terminating ventricular ectopies, and
finally, asymptomatic relatives of probands detected during electrocardiography acquisition
(early repolarization pattern). This syndrome consists of 2 phenotypes, early repolarization and
Brugada syndrome. Herein, we first describe 2 patients with early repolarization and Brugada
syndrome, then, discuss their definition, epidemiology, genetics, cellular mechanism, diagnosis,
risk stratification, and finally, therapeutic challenges and options one by one in detail.
