Morphometric Assessment of Cerebellum in Sudanese Population Using MRI

Evaluating the influence of gender and age on cerebellum is significant for pathophysiological studies of degenerative brain disorders. This study aimed to evaluate the growth rate of the cerebellum in the normal brain in Sudanese population. Materials and Methods: This cross-sectional descriptive study was performed at Modern Medical Center, Alia Specialist Hospital and Wad Medani Modern Medical Center, Sudan from 2017 to 2019. The data of 100 normal individuals with an age range of 3 months to 80 years old (males: 42%) were evaluated. A magnetic resonance imaging (MRI) was performed for all participants after applying the standard cerebellum protocol. Individuals with anomalies or abnormalities that may affect the posterior fossa were excluded. Measurement of all regions was performed in the screen monitor of MRI machine and statistically analyzed using SPSS Software version 16. Results: The mean of the right hemisphere width, right hemisphere length, left hemisphere width, left hemisphere length, maximum hemisphere width, maximum hemisphere length, anteroposterior width, and anteroposterior length was 4.38, 4.88, 4.46, 4.42, 9.73, 6.42, 4.88, and 3.54, respectively, implying that the measurement variability was important. Conclusions: There was s statistically significant correlation between cerebellum measurement with gender in left hemisphere width and maximum hemisphere width (P = 0.05 and P = 0.07, respectively). Also, there was a significant age-related reduction in left hemisphere width and length (P = 0.001 and P = 0.05, respectively).