Title of article :
Evaluation of the Probable linkage between Cytomegalovirus and Type 2 diabetes
Author/Authors :
Azadan, Negin Department of Microbiology - Islamic Azad University Shahr-e-Qods Branch, Tehran , Ferdousi, Atousa Department of Microbiology - Islamic Azad University Shahr-e-Qods Branch, Tehran , Shahhosseini, Mohammad Hasan Department of Microbiology - Islamic Azad University Shahr-e-Qods Branch, Tehran
Pages :
7
From page :
1437
To page :
1443
Abstract :
Some recent investigations, have suggested a probable linkage between cytomegalovirus (CMV) and developing diabetes. But still there is not enough literature to assess the rate of this association. To this purpose, in the present study for detecting CMV genome, serum samples of 50 type 2 diabetic patients as the test group with an optimized PCR were tested. Sex, age and A1C parameter related to this group were recorded too. The specificity of the PCR test was 100% and its sensitivity was 100 copy of the viral genome in the sample. The related results were compared with the control group that was included 50 non-diabetic participants. The CMV genome did not find in None of these 100 samples. No related effects were observed between sex or amount of A1C and association of CMV genome in these patients. However, it seems that the age parameter is effective in this regard. Comparing these participants with some other similar research suggest that this association rate is not very high and the virus only in elderly age can be considered as a probable risk factor. Thus, for managing diabetes should be more concentrated on the well-known factors such as obesity or unhealthy lifestyle.
Keywords :
Cytomegalovirus (CMV) , Type2 Diabetes (T2D) , Polymerase chain reaction (PCR)
Journal title :
International Journal of Molecular and Clinical Microbiology (IJMCM)
Serial Year :
2021
Record number :
2702827
Link To Document :
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