Title of article :
CdO/ZnO supported silver nanoparticles as a reusable heterogeneous catalyst for one-pot synthesis of new pyrrolobenzoazepines
Author/Authors :
Noushin, Annataj Department of Chemistry - Islamic Azad University Gorgan Branch, Gorgan , Varasteh-Moradi, Ali Department of Chemistry - Islamic Azad University Gorgan Branch, Gorgan , Sayyed-Alangi, Zahra Department of Chemistry - Islamic Azad University Azadshahr Branch, Azadshahr , Hossaini, Zinatossadat Department of Chemistry - Islamic Azad University Qaemshahr Branch, Qaemshahr , Arshadi, Sattar Department of Chemistry - Payam Noor University, Behshahr
Abstract :
In this study, a new, economical, environment-friendly, and green method was reported for the synthesis a family of substituted pyrrolobenzoazepines using the one-pot condensation reactions of isatin, ammonium acetate, α-haloketones, and activated acetylenic compounds in water at room temperature in the presence Ag/CdO/ZnO nanocomposites (Ag/CdO/ZnO NCs) as a new heterogeneous catalyst. For confirming the structure of synthesized nanocatalyst, uv, XRD, FESEM, and EDX analyses were utilized. Another subject in this research is an evaluation of the antioxidant power of some synthesized pyrrolobenzodiazepines by diphenyl-picrylhydrazine (DPPH) radical trapping experiment. The short time of reaction, high yields of product, simple removing of catalyst and products are some benefits of this process.
Keywords :
Ag/CdO/ZnO NCs , pyrrolobenzoazepines , Green synthesis
Journal title :
Iranian Journal of Organic Chemistry
