Title of article :
N-formylmorpholine promoted green synthesis of amide derivatives using primary amines
Author/Authors :
Ghasemi, Narges National Petrochemical Company (NPC) - petrochemical Research and Technology Company, Arak
Abstract :
The reaction between dimethyl acetylenedicarboxylate and various NH-acids in N-formylmorpholine leads to amide derivatives in excellent yields. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification and affordability of the catalyst.
Keywords :
Amide derivatives , 8-aminoquinoline , Dialkyl acetylenedicarboxylates , various NH-acids
Journal title :
Iranian Journal of Organic Chemistry