Title of article :
The Characteristics of Nitinol in Spinal Implant Manufacturing
Author/Authors :
Parsafar, Mahdis Department of Biomedical Engineering - Islamic Azad University Science and Research Branch, Tehran , Sadrnezhaad, Khatiboleslam Department of Materials Science and Engineering - Sharif University of Technology, Tehran , Hassanzadeh Nemati, Nahid Department of Biomedical Engineering - Islamic Azad University Science and Research Branch, Tehran
Abstract :
Dueto the increasingnumberof diseases related to the spine,weexpect to seemoreresearchonthe implants used in this area. These
implants should have features such as strength, fatigue resistance, chemical stability and biocompatibility, which fortunately are
seen in an alloy called nitinol. In this study, six lumbar vertebral implants were made of nitinol and these samples been studied
by some experiments such as: X-ray diffraction and biocompatibility (evaluation of cytotoxicity by MTT assay). Finally, we came
to the conclusion that the mentioned alloy with suitable microstructure is appropriate for medical applications specially as an
orthopedic implant. According to the X-ray diffraction pattern, the samples have austenitic structures in the room temperature
and the predominant phase of the porous sample is B2-NiTi. Since the sample should be biocompatible after placement in the body
and should not cause an immune system reaction, this test was also examined and the samples were tested in vitro with an MTT kit
and the biocompatibility was assessed. The results of biocompatibility tests also indicate the suitability of the implant in terms of
cellular characteristics. These properties have made this alloy superior to other alloys in orthopedic implant utilization, especially
in areas under continuous loading. It is hoped that the construction of this type of implant will pave the way for facilitating the
treatment of spinal abnormalities.
Keywords :
NiTi , Biocompatibility , Spinal Implant , Cytotoxicity
Journal title :
Journal of Clinical Research in Paramedical Sciences