Title of article :
Cu/PDA/CCE as a Sensitive Electrode for Concurrent Determination of Ascorbic Acid and Folic Acid
Author/Authors :
Rohani, Tahereh Department of Chemistry - Payame Noor University, Tehran , Mohammadi, Zia Department of Chemistry - Payame Noor University, Tehran , Bhehshti, Amirkhosro Department of Chemistry - Payame Noor University, Tehran , Hamidian, Hooshang Department of Chemistry - Payame Noor University, Tehran , Gholamhosein Zadeh, Nasrin Department of Chemistry - Payame Noor University, Tehran
Abstract :
Herein, the electrooxidation of ascorbic acid and folic acid, as two essential vitamins, on the surface of the carbon
ceramic electrode modified by polydopamine and copper (Cu/PDA/CCE) was investigated. Poly dopamine was
fabricated by applying electro deposition conditions. Initial electrochemical characteristics were performed to
study the behavior of the fabricated electrode for simultaneous detection of two biomolecules. From voltammetric
studies using the developed electrode, two separated anodic peaks for folic acid and ascorbic acid were found
promisingly for concurrent detection of the compounds. Linear calibration diagrams were obtained in the range of
0.5 to 360 μM and 0.83 to 380 μM with detection limits of about 0.031 and 0.057 μM for folic acid and ascorbic
acid, respectively. The developed electrode was applied in human urine sample analysis with satisfying results.
Keywords :
Folic Acid , Ascorbic Acid , Carbon Ceramic , Concurrent Determination , Polydopamine
Journal title :
Iranian Journal of Analytical Chemistry
