Title of article :
assessment of tools to diagnose cancer in patients with early stage breast cancer: a systematic review
Author/Authors :
pakdaman, mohsen shahid sadoughi university of medical sciences - health policy and management research center, school of public health - department of health service management, yazd, iran , dehghan, hamidreza shahid sadoughi university of medical sciences - research center of prevention and epidemiology of non communicable disease, school of public health, yazd, iran , ziadpoor, habibeh shahid sadoughi university of medical sciences - research center of prevention and epidemiology of non communicable disease, school of public health, yazd, iran , abolhasanizade, firoozeh tehran university of medical sciences - imam khomeini hospital - department of surgery, tehran, iran , namayandeh, mahdieh shahid sadoughi university of medical sciences - research center of prevention and epidemiology of non communicable disease, school of public health, yazd, iran
Abstract :
background: breast cancer is an uncontrolled and unnatural proliferation of cells in different breast tissues. the first measure to diagnose breast cancer is an examination by a surgeon followed by mammography, sonography, sampling, and other diagnosing methods. given that there are several methods to diagnose breast cancer, and most of them are quite expensive, the present systematic review compares the expenses and effectiveness of different methods to diagnose breast cancer. methods: the study was carried out as a systematic review through searching databases, i.e., pubmed, web of science, magiran, scopus, and embase for articles published from march 1999 to may 31, 2017. the research articles regarding health technology assessment and economic assessment (n = 8) were examined. results: generally, conducting mri screening and digital mammography every six months after the age of 30 are proved to be the most efficient and economical methods to screen carriers of brca (breast cancer) mutated genes. besides, implementing both the techniques simultaneously was more cost-efficient with brca1 compared to brca2. some studies have revealed that genetic tests and oncotype tests, in particular, were the most cost-efficient methods to diagnose the disease, especially in its early stages. conclusion: consequently, indexing gene expression in individuals with brca gene mutation is revealed to more cost-efficient.
Keywords :
brca1 , 2 gene , breast cancer , breast cancer diagnosis , gene expression indexing technology , cost , effectiveness
Journal title :
Evidence Based Health Policy, Management and Economics
Journal title :
Evidence Based Health Policy, Management and Economics
