prognostic factors of in-hospital mortality in adult patients with aluminum phosphide (alp) poisoning in southern iran (2014-2018)

background: the suicide with aluminum phosphide, known as rice tablet, has increased significantly. this study aimed to investigate the epidemiology of aluminum phosphide (alp) poisoning and determine the in-hospital mortality prognostic factors in adult people referring to alp poisoning to one of the main poisoning centers in southern iran. methods: this retrospective cross-sectional study (march 21, 2014, to march 21, 2018) was conducted on all adult patients ( 16 years) with alp poisoning who were referred to ali-asghar hospital (affiliated with shiraz university of medical sciences). all data were extracted from the patients’ medical files. the patients were categorized into two groups of survived and nonsurvived. univariate and multivariate logistic regression analyses were conducted to determine prognostic factors for in-hospital mortality, and odds ratios (ors) were reported. results: totally, 97 patients were enrolled in this study. the patients’ mean±sd age was 29.3±12.2 years. both study groups (survived and non-survived) were matched in most demographic and poisoning characteristics. nausea (62.9%) and vomiting (49.5%) were the most symptoms at the time of admission. castor oil (66%), n-acetyl cysteine (56.7%), and magnesium sulfate (52.6%) were the most frequent treatment in these patients. the multivariate analysis showed that age (or=1.12, 95%ci: 1.03-1.22), body temperature (or=0.02, 95%ci: 0.01-0.48), resistant acidosis (or=77.10, 95%ci: 5.05-1176.86), and taking sodium bicarbonate (or=12.35, 95%ci: 1.25-122.10) were the prognostic factors of in-hospital mortality. conclusion: the in-hospital mortality rate in patients with alp poisoning was 29.9%. age, illiteracy, body temperature, resistant acidosis, and taking sodium bicarbonate were the prognostic factors of in-hospital mortality in these patients.