Author/Authors :
mohammadi, raziyeh isfahan university of technology - department of mathematical sciences, isfahan, iran , goodarzi‑khoigani, masoomeh isfahan university of medical sciences - child growth and development research center, research institute for primordial prevention of non-communicable disease, isfahan, iran , allameh, zahra school of medicine - department of obstetrics and gynecology, iran , mazloomy mahmoodabad, saeed shahid sadoughi university of medical sciences - social determinants of health research center, school of public health - department of health education and promotion, yazd, iran , baghiani moghadam, mohammad hossein islamic azad university, firoozabad branch - department of health, firoozabad, iran , nadjarzadeh, azadeh shahid sadoughi university of medical sciences - nutrition and food security research center, school of public health - department of nutrition, yazd, iran , mardanian, farahnaz isfahan university of medical sciences - school of medicine - department of obstetrics and gynecology, isfahan, iran
Abstract :
background: some studies have shown that socioeconomic status (ses) is positively related to insulin resistance among different population groups, except for pregnant women. therefore, we examined the relationship between ses and homeostasis model assessment‑insulin resistance (homa‑ir) index as well as mediating variables. materials and methods: this study was performed on 138 primiparous healthy women at 6–10 weeks of pregnancy. the association between ses and homa‑ir was analyzed by regression analysis, and mediating variables were determined by mediation analysis. results: ses score was positively correlated with homa‑ir index [β = 0.02, t_101 = 2.20, p = 0.03, 95% ci: (0.00–0.05]. the higher percentage of mediation was related to maternal weigh (70.80%). job activity had a protective effect on the association between ses and homa‑ir (‑62.50%). the total percentage of two mediators was 25%. conclusions: the positive relationship between ses and (homa‑ir) in early pregnancy may provide a way to control this condition.
Keywords :
insulin resistance , mediation analysis , occupations , social class
