Comparison Study between the Contrast Media of Iodine and Iodine Nanoparticles in Physicochemical Properties in CT-scan Imaging

In a new study in a comparison between the contrast medium of Iodine solution which used in the computed tomography scanning (CT-Scan) and the same contrast medium after converting it to nanoparticles by Lyophilization method. The aim of this study is to reduce the different side effects which caused the micro iodine for the patients, but the iodine nanoparticles solution have good physical and chemical properties in blood medium as antioxidant reagent compared with micro-iodine, as well as the new characteristics of nano iodine solution. The micro iodine and nanoparticles were studied on laboratory animals, so the rabbits were chosen in the study to identify the time of remaining the contrast media in the different organs, so that the diagnosis was good, as in the catheter and some organs that need the contrast media to remain for a longer period. The brain, heart, liver, kidney and bladder were selected to study the contrast media at micro and nano iodine, and the results were encouraging in the use of nano iodine in the field of diagnosis by the CT-Scan imaging. It is noticed that after injected the rabbit with the iodine nanoparticles, the value of Hounsfield unit (HU) values was monitored which have the same values after one hour. Whereas, the survival of the micro contrast medium were observed with a shorter period time of survival in the studied the organs compared with the micro contrast medium. Therefore, it is recommended to using iodine nanoparticles solution to monitor the functioning of the organs.