Title of article :
SARS-CoV-2 Infection in Iranian People Living with Human Immunodeficiency Virus-1 Infection
Author/Authors :
Garshasbi ، Saba Department of Molecular Medicine - Faculty of Advanced Technologies in Medicine - Iran University of Medical Sciences , Bokharaei-Salim ، Farah Department of Virology - School of Medicine - Iran University of Medical Sciences (IUMS) , Khanaliha ، Khadijeh Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases - Iran University of Medical Sciences , Kiani ، Jalal Department of Virology - School of Medicine - Iran University of Medical Sciences (IUMS) , Kalantari ، Saeed Department of Infectious Diseases and Tropical Medicine - Iran University of Medical Sciences , Jamshidi Makiani ، Mahin Antimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases - Iran University of Medical Sciences , Marjani ، Arezoo Department of Virology - School of Public Health - Tehran University of Medical Sciences , Dehghani-Dehej ، Farzaneh Iran University of Medical Sciences , Babaei ، Roghayeh Department of Medical Nanotechnology - Faculty of Advanced Sciences and Technology - Islamic Azad University, Tehran Medical Sciences , Sadeghi ، Mohsen Iran University of Medical Sciences , Abbasi-Kolli ، Mohammad Iran University of Medical Sciences
Abstract :
Background: A novel Coronavirus first emerging in Wuhan, China, was named severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). The disease caused by SARS-CoV-2 is known as Coronavirus disease 2019 (COVID-19). HIV-1 infected individuals may be at risk of COVID-19. Objectives: This cross-sectional study evaluated the SARS-CoV-2 infection rateandCOVID-19 prevalenceamongIranian HIV-1-infected people. Methods: The study was conducted on 155 HIV-1-infected patients from June 2020 to October 2020. COVID-19 Ab (IgG) was detected using an enzyme immunoassay in serum specimens. Furthermore, nasopharyngeal and oropharyngeal specimens were collected. Then, the genomic RNA of SARS-CoV-2 was detected using a real-time polymerase chain reaction (RT-PCR). Clinical symptoms of the studied participants with and without COVID-19 were examined. Results: Of 155 HIV-1-infected individuals, 12 (7.7%) had positive real-time PCR results for SARS-CoV-2. Out of 12 (7.7%) patients with COVID-19, four (33.3%) were males. Anti-COVID Ab (IgG) was detected in 10 (6.5%) participants, of whom eight (80.0%) were males. The most common COVID-19 clinical symptoms, including dry cough, fever, runny nose, anosmia, and hypogeusia, were observed in seven (58.3%), five (41.7%), five (41.7%), five (41.7%), and five (41.7%) patients with COVID-19, respectively. Conclusions: A recent study has shown that the risk of SARS-CoV-2 infection in HIV-infected individuals is similar to that in the general population.
Keywords :
Clinical Symptoms , COVID , 19 , SARS , CoV , 2 , HIV , 1 Infection
Journal title :
Jundishapur Journal of Microbiology (JJM)
Journal title :
Jundishapur Journal of Microbiology (JJM)
