Title of article :
Prevalence of Viruses in Acute Asthma Exacerbations in Childhood in a Hospital in West Part of Turkey
Author/Authors :
Selime Ozen ، Boluk Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Taskirdi ، Ilke Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Akcal ، Omer Division of Allergy and Immunology, Department of Pediatrics - Gaziantep Cengiz Gökçek Maternity and Children’s Hospital , Kaya ، Mehmet Sirin Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Haci ، Idil Akay Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Soyoz ، Ozgen Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Celik ، Figen Celebi Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Karkiner ، Canan Sule Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Ayhan ، Fahri Yuce Department of Microbiology - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Gulez ، Nesrin Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Genel ، Ferah Division of Allergy and Immunology, Department of Pediatrics - Dr Behcet Uz Children’s Education and Research Hospital - University of Health Sciences Izmir , Can ، Demet Departments of Pediatrics - Faculty of Medicine - Balıkesir University
Abstract :
Acute asthma exacerbations (AAE) are episodes characterized by potentially life-threatening and rapidly deteriorating asthma symptoms. Viral respiratory infections are one of the major triggers in the pathophysiology of childhood asthma exacerbations. In this study, we aimed to determine the distribution of viral agents among pediatric AAE patients. One hundred and three AAE patients, aged 5 or older, hospitalized between from February 2017 through February 2020 at Pediatric Immunology and Allergic Diseases Unit were included in this study. Fifty patients (48.5%) were female, and the mean age of the patients was 108.2 months. Viruses were detected in 58 (%56.3) of the patients, in 5 of whom more than one virus type was detected. The most commonly detected virus was human rhinovirus (n=43, 67.1%). Other types included respiratory syncytial virus (n=8; 12.5%), influenza (n=6; 9.3%), human metapneumovirus (n=4; 6.2%), adenovirus (n=1; 1.5%), enterovirus (n=1; 1.5%), and parainfluenza (n=1; 1.5%). Viral agents were detected in 29 out of the 47 patients with allergic asthma, with human rhinoviruses comprising the majority (18 patients). The mean length of hospital stay was 7.89 days. Human rhinovirus is the most common virus that triggers AAE, with similar distributions in allergic and non-allergic asthma. We found no correlation between virus type and the length of hospital stay.
Keywords :
Acute asthma exacerbations , Polymerase chain reaction , Viruses
Journal title :
Iranian Journal of Allergy, Asthma and Immunology
Journal title :
Iranian Journal of Allergy, Asthma and Immunology
