Effect of RDA Protein on Renal Function in Children with Chronic Kidney Diseases

Children with chronic kidney diseases have an increased risk of progression to end-stage renal disease, which would ultimately result in lifelong disability and shortening of lifespan. There is no effective intervention such as renal replacement therapy because of high cost and donor shortage. This study aimed to examine the effect of recommended dietary allowance (RDA) protein on chronic kidney diseases (CKD) children without dialysis to halt the progression of CKD by preventing the deterioration of the renal function. In this observational study, 30 children aged 2 - 18 years at different CKD stages without dialysis were selected as the research sample. Anthropometric measurements (namely weight and height) and laboratory assessments (namely S. creatinine. blood urea, total serum albumin, hemoglobin, serum ferritin, and CCr) were considered at the beginning of the study. Following the intervention using the RDA protein during three- and six-month periods, anthropometric and laboratory assessments were compared using the preliminary data.Weight, weight for age Z score, and body mass index (BMI) significantly increased (P 0.05) after three and six months, compared to the preliminary data. Moreover, laboratory assessments such as Hb, S. creatinine, blood urea, and creatinine clearance rate significantly improved (P 0.05) after three and six months of RDA protein intake without dialysis. The growth and renal function improved following the intervention with recommended dietary allowance protein inCKDchildren without dialysis.