Title of article :
Could COVID-19 Trigger Presentation or Exacerbation of Vasculitides? (A 14-Year-Old Girl with Newly Diagnosed GPA After COVID-19 Infection)
Author/Authors :
Raeeskarami ، Reza Department of Pediatrics - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences , Mousavi ، Hosein Department of Cardiology - AJA University of Medical Sciences , Ashouri ، Mohammad Department of Surgery - Imam Khomeini Hospital - Tehran University of Medical Scienses , Akbariasbagh ، Parvin Department of Pediatrics - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences , Assari ، Raheleh Department of Pediatrics - Tehran University of Medical Sciences , Naderi ، Sahar Department of Pediatrics - Tehran University of Medical Sciences
Abstract :
Introduction: Granulomatosis with polyangiitis (GPA) is a kind of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), which involves small-to-medium-sized vessels. Besides, GPAusually involves the upper and lower respiratory tract, and also causes necrotizing glomerulonephritis. The involvement of the heart and gastrointestinal (GI) tract in GPA is unusual, and these are atypical places of this vasculitis. Case Presentation: A14-year-old girl with a newly diagnosedGPAafter afflicting with COVID-19 infection presented with ST-elevation Myocardial Infarction (MI), GI perforation, and intracranial hemorrhage. Conclusions: Although GPA is rare in the pediatric population, it might occur in this age group and could involve multiple organ systems.
Keywords :
Intracranial Hemorrhage , Gastrointestinal Perforation , Myocardial Infarction , COVID , 19 , Granulomatosis with Polyangiitis
Journal title :
Iranian Journal of Pediatrics
Journal title :
Iranian Journal of Pediatrics
