Title of article :
Green synthesis of imidazole-2-thione derivatives using ethyl 3-chloro-2-iminopropanoate
Author/Authors :
Haerizadeh, Bibi Narjes Department of Chemistry - Tarbiat Modares University - Tehran, Iran , Navabi, Atefeh Department of Chemistry - Arak University - Arak, Iran , Tizkar, Maryam Department of Chemistry - Damghan University - Damghan, Iran
Abstract :
An efficient synthesis of imidazole-2-thione was described via multicomponent reaction of isothiocyanates, ethyl 3-chloro-2-iminopropanoate and malononitrile in water at room temperature in good yields and without any catalyst.
Keywords :
Imidazole , Ethyl 3-chloro-2-iminopropanoate , Et3N , Isothiocyanate
Journal title :
Iranian Journal of Organic Chemistry
