Author/Authors :
Chavoshi, Tahereh Anesthesiology Department - Ali Asghar Children’s Hospital - Iran University of Medical Sciences, Tehran, Iran - Anesthesiology Department - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mahdavi, Alireza Anesthesiology Department - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran - Pediatric Surgery Research Center - Research Institute for Children’s Health - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Razavi, Sajad Anesthesiology Department - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Hajipour, Mahmood Department of Epidemiology, School of Public Health and Safety - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Shafa, Amir Anesthesiology Department - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mahdavi, Nastaran Sadat Anesthesiology Department - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Moshari, Mohammadreza Department of Anesthesiology - Faculty of Medicine - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
Introduction: Unfortunately, few studies have been performed on the pharmacodynamic effects of anesthesia in children suffering cerebral
palsy(CP).Patients were candidates for surgery for various reasons.
Due to the lower need for anesthesia in these children, side effects of
various anesthetic agents, adverse drug reactions, delayed awareness
and higher costs can be prevented in these children. The present study
aims to evaluate and compare the depth of anesthesia in minor surgeries
using Bispectral Index (BSI) in children suffering CP.
Materials and Methods: This cross sectional study was performed on 64
children aged two to ten years in two groups with and without cerebral
palsy in Mofid Hospital, Tehran, Iran in 2020. BIS index, mean arterial
blood pressure and heart rate were measured before and after anesthesia
induction, every ten minutes during operation, after extubation and when being able to respond to verbal stimulation.
Results: This study examined 64 patients equally divided into two study
groups “with and without cerebral palsy”. The mean BIS level in children
suffering CP was lower than children without cerebral palsy. The dosage
of isoflurane gas used for anesthesia in CP patients was meaningfully
lower than its dosage in children without cerebral palsy.
Conclusion: Monitoring of anesthesia in this study, showed that use of
BIS could reduce the use of anesthetic agents and related side effects to provide the appropriate depth of anesthesia.
