Title of article :
In vitro Free Radical Scavenging and Brine Shrimp Lethality Bioassay of Aqueous Extract of Ficus racemosa Seed
Author/Authors :
Hamid, Kaiser Department of Pharmacy - East West University , Sultana, Shapna Department of Pharmacy - Southeast University, Dhaka, Bangladesh , Urmi, Kaniz Fatima Department of Pharmacy - Jahangirnagar University, Dhaka, Bangladesh , Obayed Ullah, Mohammad School of Chemistry and Molecular Bioscience - The University of Queensland, Australia , Zulfiker, Abu Hasanat Md Department of Pharmacy - Southeast University, Dhaka, Bangladesh , Hossain, Md. Afzal Department of Pharmacy - Southeast University, Dhaka, Bangladesh
Abstract :
The present work was accomplished to explore the free radical scavenging and cytotoxic potential of the freeze-dried aqueous extract of Ficus racemosa seed using 1, 1-diphenyl-2-picrylhydrazyl (DPPH), and brine shrimp lethality bioassay method. In both methods, F. racemosa showed a significant activity. In case of free radical scavenging activity, it showed a potent radical scavenging activity with IC 50 value of 22.10 ìg/ml. The cytotoxic activity of the extract was moderate having LC50 value of 4.04 ìg/ml.
Keywords :
1 , 1 , diphenyl , 2 , picrylhydrazyl (DPPH) , Brine shrimp , Cytotoxicity , Ficus racemosa , Moraceae , Radical scavenging.
Journal title :
Jordan Journal of Biological Sciences
Journal title :
Jordan Journal of Biological Sciences
