Author/Authors :
Seddighi, Malihe Mashhad University of Medical Sciences, Mashhad, Iran , Sezavar, Majid Department of Pediatrics - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Shojaeian, Reza Department of Pediatrics - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Abbasi, Zahra Clinical Research Development Center - Mashhad University of Medical Sciences, Mashhad, Iran , Naseri, Maryam Department of Pediatrics - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Khademi, Gholamreza Neonatal Research Center - Mashhad University of Medical Sciences, Mashhad, Iran
Abstract :
Introduction: Diaphragmatic hernia is a congenital anomaly with significant mortality even in the best centers of the
world. Numerous risk factors have been identified in
studies as predictors of patient outcome. The aim of this
study was to determine the status of diaphragmatic hernia
and related outcomes in children admitted to pediatric
hospital.
Materials and Methods: Data of diaphragmatic hernia was
extracted from patients’ records in Dr. Sheikh Hospital in
Northeast of Iran who were admi ed since 2009 !ll 2019.
Demographic and birth information, disease diagnostic
findings along with developmental defects or syndromes
were recorded. In addition, more information about the
patient and surgery was collected, including the length of the patient's stay in the intensive care unit (ICU), and the
patient's condition before and after surgery. Also, data
about recurrence of the disease, postoperative growth
and development status of the child were gathered.
Results: Study included 153 pa!ents, of whom 61.4%
were male. Term gestational age, vaginal delivery,
respiratory distress, and organ defects were seen in
81.7%, 54.9%, 91.5 %, and 24.2 % respec!vely. The
overall hospital mortality of pa!ents was 24.8%.The
Apgar score of the live group was significantly higher than
that of the deceased group. The length of ICU stay before
surgery was significantly higher in the deceased
group.Pco2 levels were significantly higher before and
a#er surgery in the deceased group.HCo3 levels in the
dead group were significantly higher than that of the
living group. Conclusion: The results of our study suggested that Apgar score and VBG (venous blood gas) status were probably related to patients' outcome.
