Outcomes of Lensectomy in Hereditary Lens Subluxation

Purpose: To evaluate the results of pars plana lensectomy in patients with hereditarylens subluxation.Method: Hospital records of patients with hereditary lens subluxation who had undergonepars plana lensectomy at Labbafinejad Medical Center, Tehran-Iran from 1996 to2003 were reviewed. Patients with more than 6 months of follow up were included.Underlying disorders, best corrected visual acuity (BCVA) before and after surgery,intraocular pressure (IOP), postoperative refraction and complications were evaluated.Results: Overall, records of 87 eyes of 49 patients including 27 male and 22 female subjects were reviewed. Mean follow up duration was 20 ±18 months. Underlying disordersleading to lens subluxation included Marfan syndrome (79.5%), Weill-Marchesani syndrome(8.2%), simple ectopia lentis (8.2%), and homocystinuria (4.1%). The most commonindication for surgery was non-correctable refractive error (92.1%). Mean BCVA was1.13 LogMAR (20/250) preoperatively, which improved to 0.26 LogMAR (20/30-20/40)postoperatively (P 0.001). BCVA ≥20/40 was achieved in 82.8% of cases after surgery.Angle-supported anterior chamber intraocular lens (ACIOL) was implanted in 85.1% ofthe eyes. Prophylactic band was applied in 63 eyes (72.4%). Retinal detachment developedin four eyes (4.6%) and was successfully treated.Conclusions: Lensectomy/anterior vitrectomy with implantation of an angle-supportedACIOL in patients with hereditary lens subluxation improves vision significantly without considerable complications.