Evaluation of the Effectiveness of Mini-screw-facilitated Micro-osteoperforation Interventions on the Treatment Process in Patients with Orthodontic Treatment: A Systematic Review and Meta-analysis

Background and aim: Given that MOP is a new method, the discrepancy in the research results and its effectiveness on tooth movements and possible side effects of this method are controversial. The present study aims to evaluate the efficacy of mini-screw-facilitated micro-osteoperforation interventions on the treatment process in patients with orthodontic treatment. Materials and methods: From the electronic databases, PubMed, Cochrane Library, Embase, ISI have been used to perform systematic literature between January 2018 and July 2020. Therefore, a software program (Endnote X8) has been utilized for managing electronic titles. Searches were performed with mesh terms. The quality of the included studies has been assessed using the Cochrane Collaboration s tool. For Data extraction, two reviewers blinded and independently extracted data from the abstract and full text of the studies included. Moreover, the mean differences between the two groups (MOP and without MOP) with a 95% confidence interval (CI). The Meta analysis and forest plots have been evaluated using a software program available in the market (i.e., Comprehensive Meta-Analysis Stata V16). Results: In the electronic and manual search process, a total of 102 potentially relevant abstracts and titles were found. Finally, a total of eight publications met the inclusion criteria required by this systematic review. Mean difference was (MD, 0.56mm 95% CI 0.53, 0.60. P= 0.00) among 8 studies. Conclusion: The present study shows positive effects and statistically significant mini-screw-facilitated micro osteoperforation interventions on the treatment process in patients with orthodontic treatment.