Regulation of Metabolic Homeostasis by Reducing Selected Hepato-adipokines in Response to Three Types of Resistance Training in Men with Obesity

Introduction: Decreased physical activity is one of the main causes of the obesity epidemic. In the process of obesity, the secretion of some hepato-adipokines increases and causes metabolic disorders. Exercise plays an important role in improving the complications of obesity by regulating the levels of selected hepato-adipokine. The purpose of this study was to examine the effects of three types of resistance training methods on selected hepato-adipokine and lipid profiles in men with obesity. Materials and Methods: The sample of the study included 44 sedentary men with obesity divided into 4 groups of traditional resistance training (TRT), circuit resistance training (CRT), and interval resistance training (IRT) as well as one control group. Fetuin-A, Fetuin-B, high-density lipoproteins (HDL), low-density lipoproteins (LDL), total cholesterol (TC), and triglyceride (TG) were measured using the ELISA method. Results: The results of the mixed model ANOVA analysis showed a significant interaction between the type of training used and time at the levels of Fetuin-A (F (1, 40) = 94273.16, P = 0.001, ES = 1.00) and Fetuin-B (F (1, 40) = 49697.67, P = 0.001, ES = 0.99. In addition, within-group comparisons showed that lipid profile improved in TRT and CRT groups compared to the pretest (P = 0.001), while in the IRT group this improvement was not significant (P > 0.05). Conclusion: The result of the present study shows that three models of resistance training reduced the select hepato-adipokines level in comparison to the control group. However, IRT and CRT had the greatest effect on reducing Fetuin-A and Fetuin-B, respectively.