The Possible Role of Urinary Tract Infection in Urinary Stone Formation in Children

Background and Aim: The aim of this study was to evaluate urinary metabolic features as a risk factor in stone formation. Methods: In this case-control study, 222 children ranging from 6 months to 16 years old suffering from urolithiasis in our university hospitals in Iran in 2019-2020 were selected through random sampling and were subsequently evaluated. The research group were children with urinary stones and urinary tract infection and the control group encompassed children with urinary stones and without urinary tract infection. Data was analyzed using statistical package for social sciences (SPSS) version 16 (SPSS Inc. Chicago, IL) for windows. Results: The ratio of average amounts of calcium, magnesium, oxalate, cystine, uric acid, and citrate to creatinine showed no significant differences between the two groups. Conclusion: Urinary tract infection cannot be considered as a factor for stone formation in the urinary tract due to changes in urinary biochemical characteristics.