Author/Authors :
Takahashi, I. University of Fukui - Faculty of Engineering - Department of Applied Chemistry and Biotechnology, Japan , Nishiuchi, K. University of Fukui - Faculty of Engineering - Department of Applied Chemistry and Biotechnology, Japan , Miyamoto, R. University of Fukui - Faculty of Engineering - Department of Applied Chemistry and Biotechnology, Japan , Hatanaka, M. University of Fukui - Faculty of Engineering - Department of Applied Chemistry and Biotechnology, Japan , Uchida, H. University of Fukui - Faculty of Engineering - Department of Applied Chemistry and Biotechnology, Japan , Isa, K. University of Fukui - Faculty of Education and Regional Studies, Japan , Sakushima, A. Kyushu University of Health and Welfare - School of Pharmaceutical Sciences - Department of Pharmacognosy and Chemistry of Natural Products, Japan , Hosoi, S. KyushuUniversity of Health and Welfare - School of Pharmaceutical Sciences - Department of Pharmacognosy and Chemistry of Natural Products, Japan
Abstract :
Reaction systems peripheral to the 1:2 condensation reaction between o-phthalaldehyde and primary amine were studied. Newly identified were 1,3-dihydroxyisoindoline, o-iminomethylbenzaldehyde and o-amidiniobenzoate,the last of which exhibited moderate anticancer activity.
Keywords :
1 , 3 , dihydroxyisoindoline , o , iminomethylbenzaldehyde , o , amidiniobenzoate , anticancer activity
