Title of article :
Synthesis of Pyranoid Sugar α-Amino Acid Derivatives from 2-Oxo-Dgluconic Acid
Author/Authors :
Schmidt, Stephan Universität Leipzig - Institut für Organische Chemie, Germany , Teich, Lars Universität Leipzig - Institut für Organische Chemie, Germany , Khodja, Mohamed Universität Leipzig - Institut für Organische Chemie, Germany , Sicker, Dieter Universität Leipzig - Institut für Organische Chemie, Germany
Abstract :
Syntheses of novel sugar amino acid derivatives with the 2-amino-D-arabino-hex-2-ulopyranosonic acid skeleton are described, with the anomeric centre being the α-C-atom of the amino acid unit. The starting material for the syntheses reported is 2-oxo-D-gluconic acid which has been obtained byfermentation of D-glucose. Starting from this source differently protected pyranoid α-sugar amino acids as well as derivatives like dipeptides could be synthesized.
Keywords :
2 , oxo , D , gluconic acid , 2 , oxo , D , gluconate , sugar amino acids , 2 , amino , D , arabino , hex , 2 , ulopyranosonic acid
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
