Author/Authors :
Horváth, László University of Pécs - Department of Inorganic Chemistry, Hungary , Horváth, László MTA-PTE Research Group for Chemical Sensors, Hungary , Berente, Zoltán University of Pécs - Department of Inorganic Chemistry, Hungary , Berente, Zoltán MTA-PTE Research Group for Chemical Sensors, Hungary , Kollár, László University of Pécs - Department of Inorganic Chemistry, Hungary , Kollár, László MTA-PTE Research Group for Chemical Sensors, Hungary
Abstract :
3-Iodo-2-tropene, synthesized from the corresponding ketone (tropinone) via its hydrazone, wascarbonylated in palladium-catalyzed alkoxy- and aminocarbonylation reactions. The new synthetic approach provided the corresponding 3-carboxylic acid derivatives of pharmacological importance in chemospecific reactions and isolated in up to 87 % yields.
Keywords :
Tropane , skeleton , palladium , aminocarbonylation , alkoxycarbonylation , homogeneous catalysis
