Title of article
High-Yielding Synthesis of 3-Alkoxycarbonyl- and 3-Carboxamido-3-tropene Derivatives in Homogeneous Carbonylation Reactions of 3-Iodo-2-tropene
Author/Authors
Horváth, László University of Pécs - Department of Inorganic Chemistry, Hungary , Horváth, László MTA-PTE Research Group for Chemical Sensors, Hungary , Berente, Zoltán University of Pécs - Department of Inorganic Chemistry, Hungary , Berente, Zoltán MTA-PTE Research Group for Chemical Sensors, Hungary , Kollár, László University of Pécs - Department of Inorganic Chemistry, Hungary , Kollár, László MTA-PTE Research Group for Chemical Sensors, Hungary
From page
124
To page
127
Abstract
3-Iodo-2-tropene, synthesized from the corresponding ketone (tropinone) via its hydrazone, wascarbonylated in palladium-catalyzed alkoxy- and aminocarbonylation reactions. The new synthetic approach provided the corresponding 3-carboxylic acid derivatives of pharmacological importance in chemospecific reactions and isolated in up to 87 % yields.
Keywords
Tropane , skeleton , palladium , aminocarbonylation , alkoxycarbonylation , homogeneous catalysis
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2717824
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