Title of article :
A Very Efficient Synthesis of (1H)-1,5-Diazaanthracene-2,9,10-triones
Author/Authors :
Úbeda, J. Ignacio Universidad Complutense - Facultad de Farmacia - Departamento de Química Orgánica y Farmacéutica, Spain , Villacampa, Mercedes Universidad Complutense - Facultad de Farmacia - Departamento de Química Orgánica y Farmacéutica, Spain , Avendaño, Carmen Universidad Complutense - Facultad de Farmacia - Departamento de Química Orgánica y Farmacéutica, Spain
Abstract :
Acylation of ortho-lithiated species derived from N,O-dipivaloyl-6-amino-5,8-dimethoxy-4-methyl-2(1H)-quinolinone, followed by condensation with carbonyl reagents and in situ N-deprotection gave 7-alkyl or 6,7-dialkyl-9,10-dimethoxy-4-methyl-1,5-diaza-2(1H)-anthracenones, which were finally oxidised to the title compounds.
Keywords :
Acylation , ortho , assisted lithiation , 1 , 5 , diazaanthraquinones , Friedländer reaction , oxidative demethylation
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
