Title of article :
Enantioselective Nozaki-Hiyama Allylations Using a Multidentate Amino Alcohol as a Chiral Ligand
Author/Authors :
Rozners, Eriks Northeastern University - Department of Chemistry and Chemical Biology, USA , Fontanez, Juan Northeastern University - Department of Chemistry and Chemical Biology, USA
Abstract :
Asymmetric Nozaki-Hiyama allylations using a proline derived amino alcohol as a chiral ligand showed good enantio selectivity (er up to 90:10). The results suggest that efficient catalysts for this type of chromium-mediated reactions may be designed using multidentate ligands based on sp3 hybridized backbones.
Keywords :
Chromium , asymmetric reaction , aldehydes , homoallylic alcohols
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
