Title of article :
Synthesis of 2,3,4-Trisubstituted Chromans Via Nucleophilic Addition of N-,C-, and S-Nucleophiles to 3-Nitro-2-Trihalomethyl-2H-Chromenes.Stereochemical and Conformational Preferences
Author/Authors :
Korotaev, Vladislav Yu Ural State University - Department of Chemistry, Russian Federation , Sosnovskikh, Vyacheslav Ya Ural State University - Department of Chemistry, Russian Federation , Kutyashev, Igor B. Ural State University - Department of Chemistry, Russian Federation , Kodess, Mikhail I. Ural Branch of the Russian Academy of Sciences - Institute of Organic Synthesis, Russian Federation
Abstract :
Reactions of N-, C-, and S-nucleophiles with 3-nitro-2-trifluoro(or trichloro)methyl-2H-chromenes proceeded via nucleophilic addition at the double bond to give 2,3,4-trisubstituted chromans in good tomoderate yields. Stereochemical and conformational preferences of 2,3,4-trisubstituted chromans were studied.
Keywords :
3 , Nitro , 2H , chromenes , N , , C , , S , nucleophiles , nucleophilic addition , 2 , 3 , 4 , trisubstituted chromans
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
