Title of article :
Indium Triflate Catalysed Ene and Friedel Crafts Additions to α -Imino Esters: A One-Pot Synthesis of α-Amino Acid Derivatives
Author/Authors :
Chauhan, Kamlesh K. University of Bath - Department of Chemistry, UK , Hartley, Joseph P. University of Bath - Department of Chemistry, UK , Krakowski, Matthew University of Bath - Department of Chemistry, UK , Frost, Christopher G. University of Bath - Department of Chemistry, UK
Abstract :
The indium catalysed additions of electron-rich alkenes and heteroaromatics to an activated a-iminoester is described. The moisture-sensitive substrate is prepared in situ facilitating a convenient synthesis of unnatural a-amino acid derivatives in one-pot from commercially available reagents
Keywords :
Indium , Lewis acid , Catalysis , Friedel , Crafts , Imino , ene
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
