Title of article :
Synthesis of β-Amino Alcohols by Regioselective Ring Opening of Epoxides with Aromatic Amines Catalyzed by Tin (II) Chloride [1]
Author/Authors :
Alam, M. Mujahid Indian Institute of Chemical Technology, India , Varala, Ravi Indian Institute of Chemical Technology, India , Enugala, Ramu Indian Institute of Chemical Technology, India , Adapa, Srinivas R. Indian Institute of Chemical Technology, India
Abstract :
Tin (II) chloride dihydrate catalyses the nucleophilic ring opening of epoxide by aromatic amines leading to an efficient synthesis of b-amino alcohols in very good yields. The reactions are completely antistereoselective,highly regioselctive and proceed at ambient temperature which make this procedure particularly an alternative strategy for the synthesis of b-amino alcohols.
Keywords :
Epoxides , aromatic amines , tin (II) chloride dihydrate (SnCl2.2H2O) , b , amino alcohols
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
