Title of article :
Hydroiodination of Terminal Double Bonds Via Hydroboration or Hydrozirconation in Connection with the Total Synthesis of Fluvirucins
Author/Authors :
Freixas, Glòria Universitat de Barcelona - Facultat de Química - Departament de Química Orgànica, Spain , Urpí, Fèlix Universitat de Barcelona - Facultat de Química - Departament de Química Orgànica, Spain , Vilarrasa, Jaume Universitat de Barcelona - Facultat de Química - Departament de Química Orgànica, Spain
Abstract :
Hydroboration and hydrozirconation of 4-pentenoic acid and 4-penten-1-ol derivatives, followed byiodination in situ, have been systematically compared for the first time, looking for chemoselective,regioselective (anti-Markovnikov), efficient conversions of these alkenes to key intermediates in the total syntheses of fluvirucins.
Keywords :
Hydroiodination , hydroboration , hydrozirconation , Schwartz’s reagent , Sch 38516 , Sch 38518
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
