Author/Authors :
Mohammed Khan, Khalid University of Karachi - International Center for Chemical Sciences - H E J Research Institute of Chemistry, Pakistan , Shahzad, Sohail Anjum University of Karachi - International Center for Chemical Sciences - H E J Research Institute of Chemistry, Pakistan , Ali, Muhammad University of Karachi - International Center for Chemical Sciences - H E J Research Institute of Chemistry, Pakistan , Perveen, Shahnaz PCSIR Laboratories Complex, Pakistan , Anwar, Awais Interfakultäres Institut für Biochemie der Universität Tübingen, Germany , Voelter, Wolfgang Interfakultäres Institut für Biochemie der Universität Tübingen, Germany , Rani, Mubeen University of Karachi - International Center for Chemical Sciences - H E J Research Institute of Chemistry, Pakistan
Abstract :
A variety of 5-substituted-1,3,4-oxadiazole-2(3H)-thiones were prepared using microwave irradiationas energy source under solvent-free conditions. Reaction times were reduced from 5-14 h to 3-7 min affordinghigh yields from corresponding acyl and aroyl hydrazides.
Keywords :
5 , substituted , 1 , 3 , 4 , oxadiazolethiones , microwave , assisted synthesis
